Scientist, Avian Cell Engineering
About the Role
At Colossal Biosciences in the Biotechnology space, Restoring Earth's extinct species through cutting-edge genetic engineering and de-extinction science..
<p>The Scientist will develop novel media formulations to culture primordial germ cells (PGCs) from non-model organisms, conduct functional assays, and <em>in vitro</em> characterization of PGCs. The candidate will be part of an innovative synthetic biology platform that will develop and optimize a cell culture media platform for the production and expansion of PGCs with downstream assays to assess germline functionality from non-model avian species. This role supports Colossal’s avian program, establishing PGC lines to support conservation breeding and genetic rescue.&nbsp;</p>
<p>This position is based out of Dallas, TX, and may require some international travel. Relocation assistance is provided.</p>
<p><strong>Duties and Responsibilities:</strong></p>
<ul>
<li>Innovate and execute experiments to culture primordial germ cells (PGCs) from non-model avian organisms</li>
<li>Using a dissection microscope, collect blood and tissue from avian embryos for use in cell line derivations.</li>
<li>Test novel PGC culture conditions, sort, screen, expand PGCs according to latest protocols and newly developed approaches, particularly as it relates to the germ cell lineage</li>
<li>Interpret scRNA-seq and rt-qPCR datasets and apply this data to develop novel media formulations tailored to specific avian species</li>
<li>Work with the Avian Embryology team to develop protocols for injection of PGCs into early-stage embryos</li>
<li>Own and deliver PGC derivation and culture milestones</li>
<li>Attend lab meetings, prepare reports and presentations on the progress of projects</li>
<li>Maintain detailed, accurate laboratory records and protocols</li>
</ul>
<p><strong>Required Skills and Abilities:</strong></p>
<ul>
<li>Expert knowledge of cell culture, primary cell derivation
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View Original PostingWhat It's Like to Work at Colossal Biosciences
Systemic Collaboration
Colossal Biosciences’s positive vision for the future is rooted in our unwavering commitment to the mission of Colossal. Fueled by cutting-edge technologies in biosciences and genetics, our employees are confident in our ability to lead in the fields of de-extinction and conservation. Our optimism is not just aspirational; it’s grounded in tangible progress. In essence, our employees share a deep belief that our efforts will make a lasting impact on the world, contributing to a healthier and more sustainable planet for generations to come.
Positive Vision for the Future
Our values aren’t just words; they are the driving force behind a united effort for a healthier planet. It’s a calling for our employees to make a tangible difference for endangered species, delicate ecosystems, and the balance of nature. Our workforce finds purpose in being pioneers of the Earth, ensuring a sustainable and thriving future. Our values aren’t just words; they are the driving force behind a united effort for a healthier planet.
Alignment of Values
Ben Lamm, our CEO, embodies Colossal Biosciences values by showcasing an exceptional commitment to innovation, ethics, and environmental responsibility. His visionary leadership in the field of de-extinction has propelled Colossal to the forefront of global impact and innovation. With a deep understanding of the market and a fearless venture into complex industries, Ben anticipates organizational needs and exemplifies superior ethical conduct. His dedication to preventing the ongoing extinction event sets him apart as a visionary leader, challenging traditional conservation efforts. Beyond Colossal, Ben’s involvement in emerging technologies, space, and climate change communities, as well as memberships in prestigious organizations like the Explorer’s Club and the Planetary Society, reflects a holistic approach. His thought leadership, recognized in prominent publications, underscores his influence in innovation, technology, and entrepreneurship, aligning seamlessly with Colossal’s commitment to pushing the boundaries of what is possible.
Respect
At Colossal, we prioritize an inclusive and respectful workplace. Our open-door leadership policy encourages diverse opinions, supported by various communication channels like Slack and share-out meetings. We actively promote anonymous feedback to ensure transparency, and company-wide surveys and check-ins with HR enable employees to shape our organization collaboratively. Our commitment to respect and inclusivity is a vital part of our culture, driving innovation through our diverse team.
Killer Outcomes
At Colossal, collaboration thrives through diverse channels. Brainstorming sessions drive creative problem-solving, while monthly happy hours foster interpersonal connections. Our journal club delves into the latest scientific literature, promoting cross-disciplinary dialogue. Active Slack channels facilitate real-time communication, ensuring seamless collaboration. Monthly Lunch and Learn sessions enrich our collective knowledge base. From formal meetings to informal gatherings, our multifaceted approach ensures a dynamic and connected work environment, essential for advancing our groundbreaking work to restore earth to a healthier state.
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